If your head or body get destroyed, you will see the much dreaded death message.

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Swinging on its own, the Sword of Hope hacks into your head!
Your head is destroyed.

Everything goes dark…

You are dead.

What are YOU doing here??!??!?

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You will not be able to do any commands, except to pray.
Upon doing that, you will be teleported to sanctuary and your limbs healed to terribly injured at the least.

Note:
All items, silver, armor, and weapons will be left where your corpse is (with some exceptions), and the NPC that killed you will most likely still be aggressive towards you. So it is best to ask a friend or someone else online to retrieve your corpse (if that is not possible, at the very least heal up before doing retrieving it on your own)